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Radiopharmaceutical Therapy Registry (RaPTR)

RaPTR stands for RadioPharmaceutical Therapy Registry. RaPTR is comprised of two components—a REDCap database and MIM Cloud. REDCap hosts data on patients including disease and treatment history along with outcome and adverse events relative to radiopharmaceutical therapies. MIM Cloud—used in the RaPTR+PLUS registry—hosts de-identified PET, SPECT, and planar scans. Currently, RaPTR modules include 177Lu-dotatate, 177Lu-PSMA-617, and I-131 (for thyroid cancer) therapies.


Why RaPTR? What are the goals of the registry?

  • Establish a robust framework to collect data on patients receiving RPTs to enhance patient safety, optimize patient outcomes, and advance our field
  • Demonstrate the value of diagnostic nuclear medicine procedures and radiopharmaceutical therapies
  • Create a community of sites performing radiopharmaceutical therapies to develop and share best practices
  • Develop tools and resources, guidelines, national benchmarks, and standards to help sites improve patient outcomes
  • Utilize registry data to advocate for appropriate reimbursement for radiopharmaceutical therapies
  • Develop a robust database of patient and facility information to serve as a potential research source for future projects
  • Use imaging data to create a well annotated dataset that could be used for future AI development
  • Serve as a connection to the CMS’s Quality Payment Program (QPP)

Launch of the RaPTR Registries: Phase 1 – Pilot site testing

The RaPTR Oversite Committee (RaPTR ROC) launched Phase 1 of RaPTR and RaPTR+PLUS. Up to 10 centers from various practice settings will participate. Sites can submit clinical data in the REDCap database and image data to MIM Cloud. Image data can include pre-treatment PET scans and post-administration SPECT or planar images. RaPTR currently hosts data for 177Lu-dotatate,177Lu-PSMA-617, and I131 therapies.

For details on how to become a pilot site, review the RaPTR Onboarding Guide, or contact the Associate Director of Evidence and Quality, Julia K. Quintero-Carr, MS at  [email protected].